Increase of Severe Pulmonary Infections in Adults Caused by M1UKStreptococcus pyogenes, Central Scotland, UK

• DOI: 10.3201/eid2908.230569
• Publication Date: 2023-07-13T15:02:56Z
• Authors: Peter J.B. Davies; Clark D. Russell; Anna-Rose Morgan; Surabhi K. Taori; Diane Lindsay; Roisin Ure; Derek Brown; Andrew Smith
• Keywords: Adult; Streptococcus pyogenes; group A Streptococcus; R; Dispatch; Infectious and parasitic diseases; RC109-216; Pneumonia; 3. Good health; streptococci; Scotland; Streptococcal Infections; M1UK; Influenza, Human; necrotizing pneumonia; Medicine; Humans

We characterized the epidemiology, host-pathogen characteristics, and outcomes of severe adult pulmonary Streptococcus pyogenes infections that coincided with a high community caseload in central Scotland, UK. The pulmonary infections had high illness and death rates and were associated with socioeconomic deprivation, influenza A co-infection, and the M1UK lineage of S. pyogenes.