Evaluation of Antifibrinolytic Use in Anterior Cruciate Ligament Arthroscopic Reconstruction. A Prospective Clinical Trial

• DOI: 10.32098/mltj.02.2021.18
• Publication Date: 2021-05-27T15:54:45Z
• Authors: V. La Banca; J.G. Suzuki Leal ...; T. Protta; M. Schmidt Navarro
• Keywords: Antifibrinolytic

Objective.To evaluate the effectiveness of two antifibrinolytic drugs (tranexamic acid and epsilon-aminocaproic acid) in reducing postoperative hemarthrosis after anterior cruciate ligament reconstruction.Methods.45 patients diagnosed with primary tears were randomly placed into 3 groups: control, tranexamic (TXA) (EAC).The first group was operated on without use drugs, for other two, dose adjusted by weight.The evaluation conducted 1 7 days to assess degree hemarthrosis, visual pain scale measure range motion (ROM) degrees.The then assigned a subjective functional score at 14 28 days.Results.The TXA showed improvement compared control group.When evaluated Lysholm score, group.No significant statistical difference emerged parameter EAC group.Conclusions.The tranexamic-acid reduced improved function arthroscopic reconstruction ACL.Up this point, Epsilon-aminocaproic yielded no benefit.A follow-up study more participants may confirmation our findings or present new relevant findings.