The association between preoperative serum CEA concentrations and synchronous liver metastasis in colorectal cancer patients

• DOI: 10.3233/cbm-150561
• Publication Date: 2016-03-01T15:45:19Z
• Authors: Abbas Pakdel; Mahyar Malekzadeh; Fakhraddin Naghib...
• Keywords: Carcinoembryonic antigen; Distant metastasis

OBJECTIVE: Liver is the primary site for metastasis from colorectal cancer (CRC). It has been proposed that carcinoembryonic antigen (CEA) might have an instrumental role in development of hepatic human CRC. The aim present study was therefore to investigate assoc iation between preoperative serum CEA concentrations and incidence synchronous CRC-liver metastasis. METHODS: A total 199 patients with CRC who underwent radical surgery at Shiraz University hospitals were enrolled this study. levels without distant compared those other organs time initial diagnosis. RESULTS: Preoperative found be significantly higher metastases local (P < 0.001). Moreover, mean level liver than non-metastasis group (42.89 ng/ml vs 9.62 ng/ml) (p We did not find significant differences organ groups (p> 0.05). CONCLUSIONS: conclude high should more intensive follow-up detection