Clinical relevance of early sublingual microcirculation monitoring in septic shock patients

• DOI: 10.3233/ch-170244
• Publication Date: 2017-10-10T19:23:38Z
• Authors: Nivin Sharawy; Reham Mahrous; Sara Whynot; Ronald George; Christian Lehmann
• Keywords: Clinical Significance

Although microcirculation dysfunction plays unique role in septic shock, translation of to clinical practices is limited by current semi-quantities analysis and unclear relevance monitoring. Our aim was critically evaluate the characteristic nature relevant important microcirculation.Pubmed (2000 August 2015) were searched identify observation, case-control, intervention randomized studies evaluating relationship between alterations mortality, morbidity drug responses. The STROBE CONSORT Statement for assessment quality included studies.We examined results from 17 observations, 4 controlled trials one case report published studies. This data set comprised 637 patients. Early shock associated with hypoperfusion heterogeneous that hyperlactemia metabolic acidosis. evidence on less striking, mainly due number problems related methodological protocol currently semi-quantitative technique. In particular baseline time course alteration appears be controversial.There lack evidences importance early monitoring mechanism could