Role of TOMM40 rs10524523 Polymorphism in Onset of Alzheimer's Disease Caused by the PSEN1 M146L Mutation

• DOI: 10.3233/jad-130119
• Publication Date: 2018-06-04T10:09:42Z
• Authors: Livia Bernardi; Maura Gallo; Maria Anfossi; Maria Elena Conidi; Rosanna Colao; Gianfranco Puccio; Sabrina A.M. Curcio; Francesca Frangipane; Alessandra Clodomiro; Maria Mirabelli; Franca Vasso; Nicoletta Smirne; Raffaele Di Lorenzo; Raffaele Maletta; Amalia C. Bruni
• Keywords: PSEN1; Early-onset Alzheimer's disease

We investigated the association between TOMM40 rs10524523, age of onset, and memory performance in patients with PSEN1 M146L mutation a large familial Alzheimer's disease Calabrian kindred, wide variability onset not attributable to