First trimester maternal vitamin D, ferritin, hemoglobin level and their associations with neonatal birthweight: Result from cohort study on vitamin D status and its impact during pregnancy and childhood in Indonesia

• DOI: 10.3233/npm-180043
• Publication Date: 2019-10-08T16:41:36Z
• Authors: T. Yuniati; R.T. Dewi Judistiani; Y. Adelwin Natalia; S. Irianti; T. Husnitawati Ma...; M. Ghozali; Y. Sribudiani; A. Rengga Indrati; R. Abdulah; Budi Setiabudiawan
• Keywords: Adult; Male; Body Mass Index; Cohort Studies; Fetal Development; Hemoglobins; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Birth Weight; Humans; Prospective Studies; Vitamin D; 2. Zero hunger; Pregnancy Complications, Hematologic; Infant, Newborn; Anemia; Vitamin D Deficiency; 3. Good health; Pregnancy Complications; Pregnancy Trimester, First; Indonesia; Ferritins; Female

INTRODUCTION: Vitamin D deficiency and anemia are examples of nutritional problems global health significance. When these issues effect pregnant women, they may become a threat to the fetus’ potention for intrauterine growth. It has been known that first trimester is golden period fetal programming which influences fetuses their life after birth. This study was aiming analyze association between maternal vitamin D, serum ferritin, hemoglobin level neonatal birth weight. METHODS: From July 2016 prospective cohort women had observed in four cities West Java, Indonesia. Two hundred ninety were recuited 203 them complete follow up until delivery. Collected data included demography, blood analysis 25(OH) pregnancy weight neonates. Associations analyzed with multiple regression models. RESULTS: highly prevalent among this (approximately 75%) while found 7.5 %, little above target 5 %. However, no significant neonates, before adjustment age, pre-pregnancy body mass index, parity. CONCLUSION: There associations The negative results should not diminish benefit supplementation during pregnancy. possibility other explanatory variables influence warrants further studies.