Low caloric intake and high fluid intake during the first week of life are associated with the severity of bronchopulmonary dysplasia in extremely low birth weight infants

• DOI: 10.3233/npm-190267
• Publication Date: 2019-11-19T17:09:00Z
• Authors: Y. Al-Jebawi; N. Agarwal; S. Groh Wargo; P. Shekhawat; M.J. Mhanna
• Keywords: Bronchopulmonary Dysplasia; Fluid intake; Caloric theory; Caloric intake

OBJECTIVE:To study whether there is an association between nutritional intake during the first week of life and severity bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. METHODS:In a retrospective cohort study, medical records all ELBW infants admitted to our Neo natal Intensive Care Unit (2010–2017) were reviewed for infants' demographics, clinical characteristics, their life, BPD risk factors. RESULTS:During period 226 identified whom 67% (151/226) had moderate-severe rest served as controls. Overall with younger, smaller, spent more time on mechanical ventilation than controls [(mean±standard deviation) 24.7±1.7 vs. 26.8±2.0 weeks gestational age (p < 0.001); 678±154 837±129 grams 37.9±23.6 13.7±15.3 days 0.001) respectively]. During average caloric, carbohydrate, protein lipid intakes significantly lower, fluid was higher control group. After adjustment confounders, intake, associated odds ratio [OR (95% confidence interval)] 1.03 (1.01–1.04), 1.05 (1.03–1.07) respectively. Daily caloric increased [OR: 0.94 (0.91–0.97)]. CONCLUSION:Low high are