Myocardial ischemia in neonate with perinatal asphyxia: Electrocardiographic, echocardiographic and enzymatic correlation

• DOI: 10.32677/ijch.2017.v04.i01.002
• Publication Date: 2020-06-15T14:42:07Z
• Authors: Saira Merchant; Rajkumar M Meshram; Devendra Khairnar
• Keywords: Perinatal asphyxia; Apgar score; Neonatology; Cardiac enzymes

Objective: The objective of this study is to evaluate the presence and severity cardiac involvement in asphyxiated neonates established which clinical laboratory parameters (electrocardiogram [ECG], echocardiography [ECHO], enzyme) are reliable predictors myocardial ischemia. Design: Nested case–control study. Setting: Neonatology unit tertiary care institute. Materials Methods: group consist 90 term who had APGAR score <7 at 5 min as cases neonate >9 controls. On 2nd day life (between 24 36 h), all underwentECG, ECHO, enzyme estimation (CK-MB). Result: were divided into three groups according SARNAT scale andGroup I 25, Group II - 54, III, 11 neonates. mean gestational age was 36.97±0.35 37.12±0.46 week for controls respectively while birth weight 2.79±0.36 kg 2.68±0.76 controls, respectively. ECG changes present 70 (77.7%) cases. Grade 3 4 only III with died 1st life. Fractional shortening (FS) decreased progressively from (p<0.001) showed a significant difference between well different except versus I. Peak aortic velocity behaved similarly. Concerning acceleration, wasobserved control (all groups). CK-MB activity increased statistically seen Groups Controls Conclusion: Severe (Grades 4), elevation reduced FS can be considered marker ischemia perinatal asphyxia.