Platelet activation in patients with diabetic retinopathy

• DOI: 10.3341/kjo.2003.17.2.140
• Publication Date: 2014-11-20T08:36:29Z
• Authors: S H Bae; J Lee; K H Roh; J Kim
• Keywords: Prothrombin time; Pathogenesis; Thrombin time

To clarify the diabetic complications mediated by increased platelet activity, we undertook a study of mean component (MPC), as determined an automated hematologic analyzer (ADVIA 120, Bayer). Prothrombin time (PT), activated partial thromboplastin (aPTT), and fibrinogen were also measured to investigate blood viscosity abnormalities. MPC was in 100 healthy controls patients, latter which subdivided into no retinopathy (DR) (n = 25), nonproliferative DR 30), proliferative 45) groups. The level 26.9 g/dl control group 22.5 patients (p < 0.05). PT aPTT similar for controls; however, their corresponding levels significantly different between two groups(3.26 +/- 1.14 g/L vs. 4.21 2.35 g/L, p Our results suggest that hyperfunction may be implicated pathogenesis retinopathy.