Association between Left Ventricular Systolic Dysfunction and Mortality in Patients with Septic Shock

• DOI: 10.3346/jkms.2020.35.e24
• Publication Date: 2020-01-03T07:03:41Z
• Authors: Sua Kim; Jung-Dong Lee; Beong Ki Kim; Yong-Hyun Kim; Je Hyeong Kim
• Keywords: Association (psychology)

Background:The impact of myocardial damage on the prognosis patients with septic shock is not clearly elucidated because complex hemodynamic changes in sepsis obscure direct relationship.We evaluated left ventricular (LV) conditions that reflect independently from and their influence patients.Methods: We retrospectively enrolled 208 adult who were admitted to intensive care unit underwent echocardiography within 7 days diagnosis shock.Patients previously diagnosed structural heart disease or coronary artery excluded.Left ejection fraction (LVEF) was divided into four categories: normal, ≥ 50%; mild, 40%; moderate, 30%; severe dysfunction, < 30%.Wall motion impairment categorized following patterns: diffuse, ballooning, focal.Results: There 141 normal LVEF.Among impaired LV wall motion, diffuse pattern most common (34 patients), followed by ballooning (26 patients).Finally, 102 died, in-hospital mortality significantly higher systolic dysfunction (hazard ratio [HR], 1.97; 95% confidence interval [CI], 1.04-3.75;P = 0.039) (HR, 2.28; CI, 1.19-4.36;P 0.013) than those a function. Conclusion:Severe affected shock.Conventional echocardiographic evaluation provides adequate information development accurately predicts shock.