Early Safety Monitoring of COVID-19 Vaccines in Healthcare Workers

• DOI: 10.3346/jkms.2021.36.e110
• Publication Date: 2021-04-12T23:44:38Z
• Authors: Joon Young Song; Hee Jin Cheong; Sung Ran Kim; Sung Eun Lee; Su Hyun Kim; Ji Yun Noh; Young Kyung Yoon; Won Suk Choi; Dae Won Park; Jang Wook Sohn; Woo Joo Kim; Min Ja Kim
• Keywords: myalgia; Healthcare worker

Hospital-based surveillance for adverse events was conducted on healthcare workers after they received the first dose of coronavirus disease 2019 (COVID-19) vaccine. Among two new platform vaccines (messenger RNA- and adenoviral vector-based vaccines), rates systemic were significantly higher among adenovirus-vectored vaccine recipients. Fatigue (87.6% vs. 53.8%), myalgia (80.8% 50.0%), headache (72.0% 28.8%), fever (≥ 38.0°C, 38.7% 0%) most common recipients, but symptoms resolved within 2 days. Both types COVID-19 generally safe, serious rarely occurred.