Sarcopenia as a Predictor of Prognosis in Early Stage Ovarian Cancer

• DOI: 10.3346/jkms.2021.36.e2
• Publication Date: 2020-12-01T05:28:55Z
• Authors: Su Hyun Chae; Chulmin Lee; Sang-Hee Yoon; Seung-Hyuk Shim; Sun Joo Lee; Soo-Nyung Kim; Sochung Chung; Ji Young Lee
• Keywords: Adult; Aged, 80 and over; Ovarian Neoplasms; Sarcopenia; Adolescent; Kaplan-Meier Estimate; Middle Aged; Prognosis; 3. Good health; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Humans; Original Article; Female; Muscle, Skeletal; Tomography, X-Ray Computed; Aged; Neoplasm Staging; Proportional Hazards Models; Retrospective Studies

Background: To identify sarcopenia as a predictive prognostic factor of ovarian cancer in terms survival outcome patients with early-stage cancer.Methods: Data Konkuk University Medical Center from March 2002 to December 2017 were reviewed retrospectively.Eighty-two who underwent surgery due (International Federation Gynecology and Obstetrics stage I/II) had computed tomography (CT) images taken at the initial diagnosis included.The CT scan analyzed SliceOmatic software (TomoVision).A cutoff value was defined skeletal muscle index ≤ 38.7 cm 2 /m .Overall (OS) times compared according existence sarcopenia, subgroup analyses performed.Results: A Kaplan-Meier analysis showed significant disadvantage for when they (P < 0.001; log-rank test).Sarcopenia remained OS cancer, Cox proportional hazards model regression (HR, 21.9; 95% CI, 2.0-199.9;P = 0.006). Conclusion:This study demonstrated that cancer.Further prospective studies larger number are warranted determine extent which can be used cancer.