Emergency Cervical Carotid Artery Stenting After Intravenous Thrombolysis in Patients With Hyperacute Ischemic Stroke

• DOI: 10.3346/jkms.2022.37.e156
• Publication Date: 2022-05-10T06:47:22Z
• Authors: Doo Hyuk Kwon; Seong Hwa Jang; Hyungjong Park; Sung-Il Sohn; Jeong-Ho Hong
• Keywords: Stroke; Carotid stenting; Brain ischemia

Intravenous recombinant tissue plasminogen activator (IV rtPA) is the mainstay of treatment for acute ischemic stroke to recanalize thrombosed intracranial vessels within 4.5 hours. Emergency carotid artery stenting due steno-occlusion proximal internal (ICA) can improve symptoms, prevent neurological deterioration, and reduce recurrent risk. The feasibility safety combination therapy IV rtPA urgent have not been established. From November 2005 October 2020, we retrospectively assessed patients who had undergone emergent after hyperacute steno-occlusive ICA lesion. Hemorrhagic transformation, successful recanalization, modified Rankin Scale (mRS) score at 90 days, stent patency 3 12 months or longer were evaluated. Favorable outcome was defined as a 90-days mRS ≤ 2. Nineteen with therapy. Their median age 70 (67.5-73.5) years (94.7% men). Among 15 an additional occlusion flow restoration in ICA, TICI grade ≥ 2b achieved 11 (73.3%). transformation occurred five (26.3%); mortality rate 5.7%. Eleven (57.9%) favorable outcomes days. Stent (94.1%) maintained months. We showed that caused by atherosclerotic feasible safe.