Booster BNT162b2 COVID-19 Vaccination Increases Neutralizing Antibody Titers Against the SARS-CoV-2 Omicron Variant in Both Young and Elderly Adults

• DOI: 10.3346/jkms.2022.37.e70
• Publication Date: 2022-02-28T07:17:43Z
• Authors: Jihye Um; Youn Young Choi; Gayeon Kim; Min-Kyung Kim; Kyung-Shin Lee; Ho Kyung Sung; Byung Chul Kim; Yoo-kyoung Lee; Hee-Chang Jang; Ji Hwan Bang; Ki-hyun Chung; Myoung-don Oh; Jun-Sun Park; Jaehyun Jeon
• Keywords: Booster (rocketry); Antibody titer

Concerns about the effectiveness of current vaccines against rapidly spreading severe acute respiratory syndrome-coronavirus-2 omicron (B.1.1.529) variant are increasing. This study aimed to assess neutralizing antibody activity wild-type (BetaCoV/Korea/KCDC03/2020), delta, and variants after full primary booster vaccinations with BNT162b2. A plaque reduction neutralization test was employed determine 50% dilution (ND