Prognostic Value of Brachial-Ankle Pulse Wave Velocity According to Subjects’ Clinical Characteristics: Data From Analysis of 10,597 Subjects

• DOI: 10.3346/jkms.2023.38.e414
• Publication Date: 2023-12-13T00:17:49Z
• Authors: Hack-Lyoung Kim; Kyu-Sun Lee; Hyun Sung Joh; Woo-Hyun Lim; Jae-Bin Seo; Sang-Hyun Kim; Joo-Hee Zo; Myung-A Kim
• Keywords: Interquartile range

To make good use of the prognostic value arterial stiffness, it is important to identify population with greatest benefit. In this study, we compared brachial-ankle pulse wave velocity (baPWV) according various clinical characteristics.A total 10,597 subjects who underwent baPWV measurement (mean age, 61.4 ± 9.5 years; female proportion, 42.5%) were retrospectively analyzed. Major adverse cardiovascular events (MACEs), defined as a composite cardiac death, non-fatal myocardial infarction, coronary revascularization, and ischemic stroke assessed during follow-up period.In multivariate analysis, variables more than 4,000 selected grouping variables, which sex (men women), age (≥ 65 < years), body mass index (BMI) 25 kg/m²), hypertension (presence absence), estimated glomerular filtration rate 90 mL/min/1.73 m²), statin (user non-user). During median duration 3.58 years (interquartile range, 1.43-5.38 there 422 MACEs (4.0%). study subjects, baseline higher was associated increased risk MACE occurrence (hazard ratio for ≥ 1,800 cm/s 1,400 cm/s, 4.04; 95% confidence interval, 2.62-6.21; P 0.001). The statistically significant regardless sex, BMI, hypertension, renal function, use.Our results suggest that not only effective in specific situations, but can be effectively applied predict prognosis situations.