Comparison of cytomorphology and frozen section of endometrial aspiration with histopathology in abnormal uterine bleeding

• DOI: 10.33545/pathol.2020.v3.i3d.291
• Publication Date: 2020-11-13T06:14:46Z
• Authors: K Siva; R Jawahar; R Varadharajaperumal; J Jeya Shambavi
• Keywords: Histopathology; Curettage; Atypia; Endometrial hyperplasia; Gold standard (test); Cytopathology; Histopathological examination

Background: Endometrial aspiration cytology is the latest available modality for study of endometrial diseases. A large range diseases like atypia’s, malignancies, and infective changes can be diagnosed using a cytological examination. Aim Objectives: To assess adequacy aspirate endometrium examination correlating diagnosing efficiency with frozen section histopathology. Methods: cross sectional was conducted at department pathology, tertiary care health center in Pondicherry. Curettage were done 58 perimenopausal women abnormal uterine bleeding. sample subjected by Papanicolaou staining May- Grunewald- Gimesa staining, histopathology Hematoxalin & Eosin staining. Diagnostic accuracy compared gold standard histopathological Sensitivity, specificity predictive values calculated. Results: Among participants, mean age 45.02 ± 4.12 years. Majority (63.79%) participants had menorrhagia. High cellularity seen 58.62%. Sheets most commonly observed pattern on (65.52%). The diagnosis simple hyperplasia sensitivity 100% 94.44%in predicting HPE diagnosis. 100%in Conclusion: are useful minimally invasive techniques that utilized pathologies par