Investigation of Sodium Benzoate and Potassium Sorbate in Anti-Diabetic Herbal Drugs

• DOI: 10.33736/jaspe.4544.2022
• Publication Date: 2022-07-13T05:25:26Z
• Authors: Nazmul Islam; Md. Omar Faruque; Rausan Zamir
• Keywords: 03 medical and health sciences; UV-Vis spectrophotometric method, sodium benzoate, potassium sorbate and anti- diabetic herbal drug; 0302 clinical medicine; TJ1-1570; Mechanics of engineering. Applied mechanics; Electrical engineering. Electronics. Nuclear engineering; Mechanical engineering and machinery; TA349-359; TK1-9971

The objective of the study was to assess sodium benzoate and potassium sorbate in some anti-diabetic herbal drugs (ADHDs) collected from local markets using UV-Vis spectrophotometric method. Analytes were measured in bulk and finished drug formulations at 224 nm for Sodium benzoate and 254.5 nm for potassium sorbate. The calibration curve obeyed Beer’s law in the range of 0-40 ppm for sodium benzoate and 0-50 ppm for potassium sorbate and passed the goodness of fit evaluation. Limit of detection, LOD and limit of quantification, LOQ for sodium benzoate was 0.13 pm and 0.40 ppm respectively. The limit of detection, LOD and limit of quantification country is unknown. To conclude, whether the herbal drugs are safe to consume in terms of preservatives, more assessment is required., LOQ for potassium sorbate were 0.28 pm and 0.85 ppm respectively. No samples crossed safety limits for sodium benzoate and potassium sorbate. Overall picture of preservative content in herbal drugs of the country is unknown and, in this study, we identified both preservatives in the drug samples. To conclude, whether the herbal drugs are safe to consume in terms of preservatives, more assessment is required.