Atomic layer deposited TiO2 nanofilm on titanium implant for reduced the release of particles

• DOI: 10.3389/fbioe.2024.1346404
• Publication Date: 2024-04-26T04:58:24Z
• Authors: Xiangyu Zhao; Xiaoxuan Zhang; Zilan Zhou; Fanchun Meng; Ruilin Liu; Mengyuan Zhang; Yujia Hao; Qingpeng Xie; Xiaojun Sun; Bin Zhang; Xing Wang
• Keywords: 03 medical and health sciences; 0302 clinical medicine; titanium dioxide; atomic layer deposition; Bioengineering and Biotechnology; titanium implant; friction and corrosion; TP248.13-248.65; particles release; Biotechnology

Objective: Titanium implants are widely used in surgeries for their biocompatibility and mechanical properties. However, excessive titanium particle release can cause implant failure. This study explores Atomic Layer Deposition (ALD) to coat commercially pure (Cp-Ti) with TiO 2 , aiming improve its frictional corrosion resistance while reducing release. By comparing films varying ALD cycle numbers, we assess surface properties, release, friction, performance, providing insights into mitigating from implants. Methods: Cp-Ti surfaces were prepared coated of 100, 300, 500 cycles. Surface characterization involved SEM, EDX, XRD. Friction was tested using nanoindentation, ICP-MS. Corrosion evaluated through immersion tests electrochemical analysis. Cytotoxicity assessed BMSCs. Results: revealed smoother increased cycles, confirming successful deposition. testing showed reduced friction coefficients higher supported by nanoindentation results. improved increasing as evidenced studies no significant cytotoxic effects. Conclusion: ALD-coated significantly enhance The underscores the importance numbers optimizing film offering designing