Exploring advanced Drosophila cell death techniques and cancer-related studies

• DOI: 10.3389/fceld.2024.1478258
• Publication Date: 2024-11-26T04:25:43Z
• Authors: Daniel Tendero-Lopez; Maria Dominguez; Mary Luz Uribe
• Keywords: 0303 health sciences; Sensors; QH301-705.5; -omics; Development; sensors; methods; 03 medical and health sciences; Methods; cancer; Drosophila; Biology (General); programmed cell death; development; Programmed cell death; Cancer

Cell death is an essential physiological process for the survival of multicellular organisms. Our understanding programmed cell in development, immune function maintenance, and adult tissue repair has significantly advanced over past decade. However, there are still gaps our knowledge about induction, regulation, checkpoints this due to diverse forms cellular suicide rapid nature process. Molecular advancements such as specific sensors, RNA-seq, single-cell proteomics have allowed identifying new factors a better molecular networks pathways that regulate these processes. Programmed also plays role cancer, both limiting facilitating aspects malignant process, making its analysis inhibition challenging. This review discusses field’s using model organism Drosophila melanogaster , types development tissues, techniques studying it, cancer.