A rapid and ultra-sensitive dual readout platform for Klebsiella pneumoniae detection based on RPA-CRISPR/Cas12a

• DOI: 10.3389/fcimb.2024.1362513
• Publication Date: 2024-06-27T04:40:32Z
• Authors: Meiying Tan; Lina Liang; Chuan Liao; Zihan Zhou; Shaoping Long; Xueli Yi; Chunfang Wang; Caiheng Wei; Jinyuan Cai; Xuebin Li; Guijiang Wei
• Keywords: DNA, Bacterial; 0303 health sciences; Endodeoxyribonucleases; Cas12a; CRISPR-Associated Proteins; Microbiology; Sensitivity and Specificity; QR1-502; Klebsiella Infections; Recombinases; Klebsiella pneumoniae; 03 medical and health sciences; Cellular and Infection Microbiology; Molecular Diagnostic Techniques; Bacterial Proteins; Limit of Detection; CRISPR; lateral flow strip; Humans; Clustered Regularly Interspaced Short Palindromic Repeats; recombinase polymerase amplification; CRISPR-Cas Systems; Nucleic Acid Amplification Techniques

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