Comparison of Coronary Artery Bypass Grafting and Drug-Eluting Stent Implantation in Patients With Chronic Kidney Disease: A Propensity Score Matching Study

• DOI: 10.3389/fcvm.2022.802181
• Publication Date: 2022-04-01T05:16:46Z
• Authors: Yang Li; XueJian Hou; TaoShuai Liu; Shijun Xu; Zhuhui Huang; XiaoYu Xu; Ran Dong
• Keywords: Interquartile range; Clinical endpoint

To compare the long-term outcomes of coronary artery bypass grafting (CABG) vs. percutaneous intervention (PCI) with drug-eluting stents (DESs) for disease (CAD) patients chronic kidney (CKD).Coronary decreased function (estimated glomerular filtration rate <60 ml/min/1.73 m2) who underwent CABG (n = 533) or PCI DES 952) from 2013 to 2020 were enrolled at a single center. The baseline characteristics and clinical compared between groups each matched pair CKD. primary endpoint was occurrence all-cause death. secondary endpoints major adverse cardiovascular events (MACCEs) such as death, myocardial infarction (MI), stroke, repeat revascularization.A total 1,485 revascularization, 533 952 PCI. median follow-up duration 55.6 months (interquartile range 34.3-74.7 months). Multivariable Cox regression models used risk adjustment, after propensity score matching (PSM), 399 well in group. in-hospital mortality group higher than that group, but difference not statistically significant (5.0 2.5%, p 0.063). At 1-year follow-up, associated lower survival (94.2 98.0%, hazard ratio [HR] 3.72, 95% CI 1.63-8.49, < 0.01). end 5-year freedom MI repeated revascularization both better (89.1 81.7%, HR 0.59, 0.38-0.92, 0.019; 86.9 73.8%, 0.54, 0.36-0.81, 0.003, respectively). Furthermore, MACCEs also (58.5 51.3%, 0.71, 0.55-0.91, 0.030). had cumulative (68.4 66.0%) without (HR 0.92, 0.67-1.27, 0.602) PCI.Compared use stent among CKD, rate, number during follow-up. 1 year, other comparable two cohorts, showed