Sub-satisfactory recanalization of severe middle cerebral artery stenoses can significantly improve hemodynamics

• DOI: 10.3389/fcvm.2022.922616
• Publication Date: 2022-09-29T10:59:16Z
• Authors: Kun Zhang; Wei Ren; Tian-Xiao Li; Zi-Liang Wang; Bu-Lang Gao; Jin-Chao Xia; Hui-Li Gao; Yong-Feng Wang; Jian-Jun Gu
• Keywords: Digital subtraction angiography

Purpose To investigate the effect of sub-satisfactory stent recanalization on hemodynamic stresses for severe stenoses middle cerebral artery (MCA) M 1 segment. Materials and methods Patients with MCA M1 segment treated endovascular angioplasty were retrospectively enrolled. Three-dimensional digital subtraction angiography before after stenting was performed; computational fluid dynamics (CFD) analysis at stenosis normal segments proximal distal to analyzed. Results Fifty-one patients enrolled, length ranging from 5.1 12.8 mm (mean 9 ± 3.3 mm). Stent successful in all (100%) patients. The immediately demonstrated a significant ( P < 0.05) decrease comparison (31.4 ±12.5% vs. 87.5 9.6%), residual 15–30% 22.4 3.5%). Before stenting, total pressure significantly higher 0.0001), while WSS, velocity, vorticity decreased 0.0001) arterial stenosis, pressure, compared those stenosis. After recanalization, or perforator root improved similar virtual removal. Conclusion Sub-satisfactory can improve status perfusion stenoses.