Cardiac resynchronization therapy in heart failure patients by using left bundle branch pacing

• DOI: 10.3389/fcvm.2022.990016
• Publication Date: 2022-08-23T05:57:53Z
• Authors: Ying Gu; Yanming Li; Ying Zhu; Xiuyu Lin; Tian Tian; Qigao Zhang; Jianbin Gong; Lei Wang; Jianhua Li
• Keywords: Bundle branch block

Left bundle branch pacing (LBBP) is emerging as an effective alternative to achieve cardiac resynchronization therapy (CRT) and improve heart function. The purpose of our study was investigate the feasibility efficacy LBBP in failure patients with left ventricular ejection fraction (LVEF) <50% block (LBBB).All complete LBBB LVEF were retrospectively included from April 2018 2021 underwent CRT via implantation. ECG, parameters, New York Heart Association (NYHA) functional class, echocardiographic measurements, complications recorded analyzed at implant during follow-up 1, 6, 12 months.Left successful all 34 (mean age 65.6 ± 11.2 years, 67.6% men). A significant decrease QRS duration (QRSd) observed after operation for 1 month (153.2 1.7 vs. 111.9 2.6 ms, p < 0.01). LBB capture threshold R-wave amplitude remained stable 12-month when compared implantation values (0.62 0.13 V @ 0.4 ms 0.73 0.21 12.02 5.68 mV 8.58 4.09 mV, respectively). increased significantly (35.28 1.70% 51.09 1.71%, 0.01) accompanied reduced end-diastolic dimension (LVEDd; 65.3 1.99 53.58 2.07 mm, atrial (LAD; 49.03 1.32 40.67 1.58 Normalized (LVEF ≥ 50%) found 70.5% months. NYHA classification, brain natriuretic peptide (BNP), 6-minute walk test (6MWT) improved months (all 0.01 baseline). No deaths or hospitalizations period.The current work suggested that feasible a high success rate correct structure function low threshold.