Obesity, malnutrition, and the prevalence and outcome of hypertension: Evidence from the National Health and Nutrition Examination Survey

• DOI: 10.3389/fcvm.2023.1043491
• Publication Date: 2023-03-02T06:42:16Z
• Authors: Heng-Zhi Zhang; Yi-Han Wang; Ying-Lin Ge; Shu-Yu Wang; Jin-Yu Sun; Lu-Lu Chen; Shuang Su; Ying Sun
• Keywords: 2. Zero hunger; obesity; hypertension; double burden of malnutrition; RC666-701; Diseases of the circulatory (Cardiovascular) system; malnutrition; Cardiovascular Medicine; 16. Peace & justice; waist circumference; 3. Good health

Nutritionally unhealthy obesity is a newly introduced phenotype characterized by combined condition of malnutrition and obesity. This study aims to explore the influence nutritional status on prevalence outcome hypertension.Participants collected from National Health Nutrition Examination Survey (NHANES) database were divided into four subgroups according their conditions, as defined waist circumference serum albumin concentration. The lean-well-nourished was set reference group. Logistic regression models applied evaluate hypertension risk. Kaplan-Meier analysis Cox proportional hazard used assess survival curve risk participants with hypertension.A total 28,554 10,625 patients included in analysis. lean-malnourished group showed lower (odds ratio [OR] 0.85, 95% confidence interval [CI]: 0.77-0.94), while obese-well-nourished elevated (OR 1.47, CI: 1.3-1.67). Two malnourished groups had higher mortality risks (HR 1.42, 1.12-1.80 HR 1.31, 1.03-1.69 for lean obese, respectively) than 1.02, 0.76-1.36) similar lean-well-nourished.Malnutrition associated developing both obese participants, but it worse once present. highest all-cause followed obese-malnourished. patients.