Storage duration of vitrified embryos does not affect pregnancy and neonatal outcomes after frozen-thawed embryo transfer

• DOI: 10.3389/fendo.2023.1148411
• Publication Date: 2023-03-14T06:04:46Z
• Authors: Xuelan Li; Pingping Guo; Christophe Blockeel; Xinning Li; Ling Deng; Jie Yang; Chujun Li; Min Lin; Haocun Wu; Guifeng Cai; Yunzhao Hu; Xin Chen
• Keywords: Live birth; Embryo cryopreservation

Background With the refinement of cryopreservation technology, number frozen-warmed embryo transfer (FET) cycles and cryopreserved embryos has increased rapidly. However, studies investigating effect storage duration on pregnancy outcomes after vitrification are limited their results controversial. Furthermore, available did not take patients’ demographic nor clinical treatment characteristics into account cryo-storage was short. So this study aimed to explore vitrified warmed neonatal in patients with good prognosis long embryos. Methods This a bi-centre, retrospective including 1037 women undergoing first FET following fresh cycle from January 2012 until December 2021. Patients were divided four groups accordance transferred (612 group I, between 1 6 months; 202 II, 7 12 141 III, 13 36 76 IV, 37 84 months). The compared amongst different groups. Results Amongst groups, no significant differences observed outcomes, biochemical rate, implantation ongoing rate live birth rate. In addition, evidence terms preterm birth, length low birthweight. Conclusions impaired by up years.