Effects of stellate ganglion block on perimenopausal hot flashes: a randomized controlled trial

• DOI: 10.3389/fendo.2023.1293358
• Publication Date: 2023-11-28T10:11:07Z
• Authors: Ying Li; Jia Chang; Gaoxiang Shi; Wenjing Zhang; Hui Wang; Lingyun Wei; Xiaochun Liu; Weiwei Zhang
• Keywords: Hot flash

Background Hot flashes are common symptoms afflicting perimenopausal women. A stellate ganglion block (SGB) is believed to be an effective treatment for hot flashes; however, more evidence needed evaluate its safety and efficacy in relieving flashes. Objective To investigate the of SGB Methods randomized controlled trial was conducted at Shanxi Bethune Hospital. Forty women with were recruited from April 2022 November randomly assigned receive either 6 consecutive treatments or saline placebo treatments. The primary outcome change flash symptom score baseline 12 weeks after treatment. secondary outcomes post-treatment Kupperman Index (KI) Pittsburgh Sleep Quality (PSQI) scores. Results Of 40 subjects, 35 completed study. All variables significantly improved. During follow-up, scores, Menopause Scale scores decreased significantly. Two subjects group experienced transient hoarseness, incidence related adverse events 10%. No occurred control group. Conclusion Compared treatment, a safe nonhormone replacement therapy that relieved effectively improved sleep quality. Additional studies assess long-term this therapy.