Hypoparathyroidism following total thyroidectomy: high rates at a low-volume, non-parathyroid institution

• DOI: 10.3389/fendo.2024.1330524
• Publication Date: 2024-01-18T17:30:57Z
• Authors: Ali Abood; Therese Ovesen; Lars Rolighed; Frédéric Triponez; Peter Vestergaard
• Keywords: Hypoparathyroidism; Parathyroid gland; Autotransplantation

Background Hypoparathyroidism following total thyroidectomy is globally the most common complication to thyroid surgery. The reported rates vary widely and might be highly dependent on surgical experience. In this study we aimed evaluate rate of hypoparathyroidism primary at a low-volume institution that only performs surgery does not have any experience with parathyroid Methods Retrospective cohort study. All patients undergoing ENT-Department, Goedstrup Hospital, Denmark, over 5-year period (2016-2020) were identified through procedure codes for thyroidectomy. Medical records, pathology reports, biochemical medical histories fully assessed each patient. endpoint was hypoparathyroidism- both immediate permanent. Secondary outcomes gland identification rates, autotransplantation, inadvertent excision. Results A 89 included in final analysis. 33 (37.1%) experienced surgery, while 30 (33.7%) still active vitamin D two months postoperatively. One year 28 (31.5%) considered as having permanent hypoparathyroidism. Sixty-one percent glands intraoperatively, 19% autotransplantation. Inadvertent excision occurred 21% associated significantly increased risk (RR = 2.99; 95% CI: 1.36 – 6.62, p 0.005). Conclusion Both transient low-volume, non-parathyroid much higher frequencies than previously reported. elevated likely due nature surgeons which part mirrored low identifications high autotransplantation