The rising death burden of atrial fibrillation and flutter in low-income regions and younger populations

• DOI: 10.3389/fepid.2023.1122790
• Publication Date: 2023-06-05T04:50:12Z
• Authors: Ye-Mao Liu; Wenxin Wang; Xingyuan Zhang; Fang Lei; Juan-Juan Qin; Xuewei Huang; Ruyan Li; Lijin Lin; Mingming Chen; Yan-Xiao Ji; Peng Zhang; Xiao-Jing Zhang; Zhi-Gang She; Jingjing Cai; Chengsheng Xu; Zhengjun Shen; Hongliang Li
• Keywords: global burden of disease; 0302 clinical medicine; prevention; early death; Epidemiology; Infectious and parasitic diseases; RC109-216; metabolic risk factors; atrial fibrillation and flutter

The aim of the study was to depict global death burden atrial fibrillation and/or flutter (AFF) between 1990 and 2019 predict this in next decade. We retrieved annual data on cases rates AFF from Global Burden Disease (GBD) Study projected trends for 2020-2029 by developing Bayesian age-period-cohort model. number deaths increased 117,038.00 315,336.80 2019. This is reach 404,593.40 2029. age-standardized mortality (ASMRs) have significantly low- middle-sociodemographic index (SDI) regions, which will surpass that high SDI regions above 4.60 per 100,000 Globally, women a higher ASMR than men, largely attributed disproportionately men lower regions. Notably, AFF-related premature continues worsen worldwide. A pandemic systolic blood pressure body mass (BMI) contributes AFF-associated death. In particular, middle-SDI younger populations are increasingly affected rapidly growing current future risk BMI. low-income countries generations not been sufficiently controlled past continue future, metabolic risks, particularly There an urgent need implement effective measures control mortality.