Comparison between 10 and 12 mg doses of intrathecal hyperbaric (0.5%) bupivacaine on sensory block level after first spinal failure in cesarean section: A double-blind, randomized clinical trial

• DOI: 10.3389/fmed.2022.937963
• Publication Date: 2022-10-04T05:08:50Z
• Authors: Nahid Manouchehrian; Farshid Rahimi-Ba...; Azar Pirdehghan; Fatemeh Shahmoradi
• Keywords: Intrathecal

Reducing adverse effects during cesarean delivery and improving the quality of sensory blocks with appropriate doses intrathecal hyperbaric bupivacaine can play an important role in safe management delivery. The aim this study was to compare 10 12 mg 0.5% on block level after first spinal failure section (CS).In double-blind, randomized clinical trial, 40 candidates CS class I-II based American Society Anesthesiologists (ASA) were randomly assigned into two equal groups (n = 20). Group A B received anesthesia (0.5%), respectively. Maximum levels block, motor quality, vital signs measured by 60 min SPA. Incidence SPA complications surgery also recorded. Data analyzed SPSS ver.21 software using repeated measures analysis variance at 95% confidence interval (CI) level.Excellent complete achieved all participants (100%). However, mean time onset (4.47 ± 0.69 vs. 3.38 0.47, P < 0.001) reach T10 (60.73 11.92 79.00 19.21, A, significantly shorter than patients B. incidence hypotension (P 0.001), nausea/vomiting 0.007) bradycardia 0.012) as well administration ephedrine atropine higher compared A.Spinal be safely a caesarean initial failure.[https://en.irct.ir/trial/40714], identifier [IRCT20120915010841N20].