Effects of saponins Rb1 and Re in American ginseng combined intervention on immune system of aging model

• DOI: 10.3389/fmolb.2024.1392868
• Publication Date: 2024-03-28T05:20:22Z
• Authors: Mao Shi; Jie Ma; Shan Jin; Tienan Wang; Yuhan Sui; Lina Chen
• Keywords: American ginseng

Aging is a major risk factor for the development of many pathological processes, such as reduced immunity, cancer, cardiovascular diseases or neurodegenerative diseases, while age-related chronic are most common causes death. This paper studies effects American ginseng saponin Rb 1 and Re alone combined intervention on immune system aging mouse models, by using 30 mg/kg , 15 Re, + (30 (co-intervention) was used to intervene in model, indicators thymus index, spleen interleukin interferon were detected evaluate impact function. The results show that can increase index 7%–12% 12%–19% model. After intervened, apoptotic cells slightly reduced, proportion reduced. combination promote 23.40% 25.5% respectively, which more advantageous than alone. In addition, reduce level INF comparable young mice. not only content, but also TNF content. above delay decline two significantly better individual recovery system. provide theoretical basis data support nutritional supplements its application groups products improve immunity.