Physical activity is a potential measure of physical resilience in older adults receiving hemodialysis

• DOI: 10.3389/fneph.2022.1032468
• Publication Date: 2023-01-06T15:34:44Z
• Authors: Anika Lucas; Jeanette Rutledge; Richard Sloane; Katherine Hall; Ciara Green; Carl Pieper; Cathleen Colón-Em...; Rasheeda Hall
• Keywords: Stressor; Activity monitor

Background Physical resilience, or the ability to recover after a physical stressor, declines with aging. Efforts preserve resilience in older dialysis population are critically needed; however, validated, patient-centered measures that sensitive change also needed. Our objective was assess accelerometer-derived step count variability, measure of intra-individual variation activity, as potential among adults receiving hemodialysis. Methods Community-dwelling ambulatory in-center hemodialysis were prospectively enrolled. Participants wore wrist accelerometers during daytime hours on both and non-dialysis days up 14 days, feasibility accelerometer use assessed from wear time. We used data compute counts 4-hour blocks variability. function Short Performance Battery (SPPB which includes gait speed test), grip strength, activities daily living (ADLs) instruments, life space mobility. interval fatigue (subjective rating 0 10) self-reported recovery correlations variability fatigue. Results Of 37 enrolled participants, 29 had sufficient for analyses. Among mean (SD) age 70.6(4.8) years, 55% (n=16) male 72% (n=21) Black race. largely sedentary median (Q1-Q3) total kilocalories per week 200 (36–552). Step positively correlated function: SPPB (r=0.50, p<0.05), (r=0.59, handgrip strength (r=0.71, Instrumental ADLs (r=0.44, p<0.05) mobility (r=0.54, p<0.05).There weak inverse correlation between post-dialysis (4-hour session) [r=-0.19 (n=102, p=0.06). Conclusions activity assessment via is feasible function, so it may be novel resilience. Further studies needed validate this measure.