Contributing Factors and Evolution of Impulse Control Disorder in the Luxembourg Parkinson Cohort

• DOI: 10.3389/fneur.2020.578924
• Publication Date: 2020-11-12T05:58:32Z
• Authors: Sylvia Binck; Claire Pauly; Michel Vaillant; Geraldine Hipp; Manon Gantenbein; Rejko Krueger; Nico J Diederich
• Keywords: Impulse control; Impulse control disorder

Background: To establish the frequency of impulse control disorder (ICD) in Parkinson's disease (PD). Methods: Within Luxembourg Study, PD patients were evaluated for ICD presence (score ≥ 1 on MDS-UPDRS I item 1.6), use dopamine agonists (DA) and other medications. Results: 470 enrolled. Among 217 without DA use, 6.9% scored positive ICD, vs. 15.4% among 253 with ( p = 0.005). The regression analysis showed that age at diagnosis had only a minor impact occurrence, while there was no influence by gender or co-medications. longitudinal study over 2 years 156 demonstrated increasing users Conclusion: This large non-interventional confirms treatment show higher than use. It newly demonstrates can develop independently from age, gender,