Language reorganization patterns in global aphasia–evidence from fNIRS

• DOI: 10.3389/fneur.2022.1025384
• Publication Date: 2023-01-06T15:50:03Z
• Authors: Haozheng Li; Jianju Liu; Shan Tian; Shunjuan Fan; Tingwei Wang; Hong Qian; Gang Liu; Yulian Zhu; Yi Wu; Ruiping Hu
• Keywords: Supramarginal gyrus; Functional near-infrared spectroscopy; Middle temporal gyrus; Supplementary motor area; Stroke; Aphasiology

Exploring the brain reorganization patterns associated with language recovery would promote treatment of global aphasia. While functional near-infrared spectroscopy (fNIRS) has been widely used in study speech and impairment, its application field aphasia is still limited.We aimed to identify cortical activation patients during naming repetition tasks.We recruited post-stroke from Department Rehabilitation Medicine at Huashan Hospital. These individuals were diagnosed without cognitive impairments, as assessed by speech-language pathology evaluations. Age- sex-matched healthy controls greater Shanghai area. During fNIRS measurement, completed picture-naming phrase task. Cortical on each these tasks then compared between groups.A total nine 14 included this study. Compared subjects, showed increased left Broca's area, middle temporal gyrus (MTG), superior (STG), pre-motor supplementary motor cortex (SMA) (p < 0.05) Furthermore, latency oxyhemoglobin (HbO) concentration supramarginal (SMG) region had a strong negative correlation their score task 0.01). In task, decreased was detected SMA SMG relative controls.The plays critical role function aphasia, especially abilities name repeat. promising approach revealing changes activities we believe it will contribute deeper understanding neurological mechanisms establishment novel for