Admission Serum Calcium Level and Short-Term Mortality After Acute Ischemic Stroke: A Secondary Analysis Based on a Norwegian Retrospective Cohort

• DOI: 10.3389/fneur.2022.889518
• Publication Date: 2022-06-15T07:37:33Z
• Authors: Yuzhao Lu; Xin Ma; Kiarash Tazmini; Ming Yang; Xiaobing Zhou; Yang Wang
• Keywords: Norwegian; Stroke

Background Disturbed serum calcium levels are related to the risk of stroke. However, previous studies exploring correlation between and clinical outcome ischemic stroke (IS) have shown inconsistent results. Object The study aimed investigate relationship admission 30-day mortality in patients with IS. Methods A total 876 IS from a Norwegian retrospective cohort were included for secondary analysis. exposure variable primary albumin-corrected (ACSC) at baseline all-cause within 30 days after first admission, respectively. Multivariable logistic regression analysis was used estimate according ACSC levels. Moreover, potential presence non-linear evaluated using two-piecewise linear smoothing function threshold level stability results by unadjusted adjusted models. Results result multiple showed that positively associated incidence adjusting confounders (age, gender, glucose, hypertension, atrial fibrillation/atrial flutter, renal insufficiency, heart failure, chronic obstructive pulmonary disease, pneumonia, paralysis, aphasia) (OR = 2.43, 95% CI 1.43–4.12). When translated into categorical variable, ORs CIs second fourth quartile vs. 1.23 (0.56, 2.69), 1.16 (0.51, 2.65), 2.13 (1.04, 4.38), respectively ( P trend 0.03). curve-fitting revealed mortality. Conclusion is patients, them linear.