Diffusion-weighted imaging hyperintensities during the chronic stage of intracerebral hemorrhage with surgery: A new clinical situation or post-surgery artifact?

• DOI: 10.3389/fneur.2022.948828
• Publication Date: 2022-09-16T05:20:40Z
• Authors: Xiaoyan Chen; Ying Li; Shengli Guo; Xun Han; Ruozhuo Liu; Chenglin Tian; Rongtai Cui; Zhao Dong; Shengyuan Yu
• Keywords: diffusion-weighted imaging; extracellular methemoglobin; chronic stage; intracerebral hemorrhage; 3. Good health; surgery; 03 medical and health sciences; 0302 clinical medicine; Neurology; Neurology (clinical); Neurology. Diseases of the nervous system; RC346-429

Background and objective Diffusion-weighted imaging (DWI) hyperintensities were occasionally seen at previous hematoma in patients several months after intracerebral hemorrhage with surgery. Whether they are newly occurred clinical situations or post-surgery changes is unknown. This study aims to investigate the prevalence possible mechanisms for this phenomenon. Methods We retrospectively reviewed MRI database surgery 3 of disease onset our hospital. also prospectively performed repeated multimodal scans two chronic stage hemorrhage. Results found that 14 out 23 (60.9%) had DWI site All lesions hyperintense on T1- T2-weighted imaging, most which appeared long narrow shape. The usually located adjacent thin wall cavity close lateral ventricle. They more associated basal ganglia than lobar ( P = 0.02) frequently those intraventricular without 0.02). Prospectively exams revealed unchanged hyperintensity during 18- 2-month follow-up, respectively. Conclusion commonly would persist years. hypothesized a mechanism by extracellular methemoglobin “islands” formed delayed no absorption macrophages from residual brain tissue. Unnecessary further examinations treatment be avoided realizing