Safety and effectiveness of thermal radiofrequency applied to the musculocutaneous nerve for patients with spasticity

• DOI: 10.3389/fneur.2024.1369947
• Publication Date: 2024-06-11T16:52:58Z
• Authors: Sergio Otero-Vill...; Jacobo Formigo-Co...; Rosa Martin-Mourelle; Antonio Montoto-M...
• Keywords: musculocutaneous nerve; radiofrequency; 0302 clinical medicine; Neurology; disabilility; thermal radiofrequency ablation; spasticity; Neurology. Diseases of the nervous system; RC346-429; 0305 other medical science

ObjectiveEvaluate safety and effectiveness of thermal radiofrequency in the musculocutaneous nerve in patients with focal elbow flexor spasticity.DesignAmbispective observational follow-up study. Patients with focal spasticity secondary to central nervous system injury with elbow flexor pattern who received thermal radiofrequency treatment in the musculocutaneous nerve between 2021 and 2023 were included.Subjects12 patients.MethodsUltrasound-guided thermal radiofrequency was applied to the musculocutaneous nerve at 80°C for 90 s. Effectiveness was assessed prior to thermal radiofrequency and at 6 months using scales to measure pain (VAS), spasticity (MAS), disability (DAS), quality of life (SQol-6D), patient-perceived and physician-perceived satisfaction (PIG-C, PGA), and goal attainment (GAS). Elbow joint range of motion was evaluated via goniometry. Safety was evaluated by assessing side effects.ResultsPatients had statistically significant improvements in spasticity (p = 0.003), severe elbow flexion (p = 0.02), pain (p = 0.046), functioning (p < 0.05), and spasticity-related quality of life (p < 0.05 in three sections). Furthermore, treatment goals were attained. Patient- and physician-perceived clinical improvement was achieved. Regarding side effects, two patients had dysesthesia that was self-limiting, with maximum duration of 1 month.ConclusionThermal radiofrequency in the musculocutaneous nerve can be a safe, effective treatment for patients with severe spasticity with an elbow flexor pattern.