High lactic acid levels in the brain contribute to the generation of focal slowing on the electroencephalogram

• DOI: 10.3389/fneur.2024.1393274
• Publication Date: 2024-04-17T04:34:26Z
• Authors: Dmitry Alexandrov...; Polina Alekseevna...
• Keywords: Brain tissue; EEG-fMRI

Focal slowing on the EEG is often associated with structural pathology of brain. Despite clinical significance focal slowing, actual electrochemical mechanisms underlying this phenomenon are still poorly understood. This paper briefly reviews role lactate in pathogenesis brain disorders that primarily related to slowing. An attempt made trace hypothetical link between pattern and cerebral tissue lactacidosis.