The Function of the Autonomic Nervous System in Asian Patients With Chronic Migraine

• DOI: 10.3389/fnins.2022.773321
• Publication Date: 2022-04-14T11:48:58Z
• Authors: Min Shi; Danqing Luo; Jun Guo; Dongdong Yang; Zhaoying Li; Huan Zhao
• Keywords: Pupillary light reflex; Pupillary reflex; Cold pressor test; Chronic Migraine

The pathogenic mechanisms underlying the autonomic nervous system (ANS) dysfunction in patients with chronic migraine (CM) remain unclear. This study investigated pathogenesis of ANS this population.A total 60 diagnosed CM and healthy subjects were recruited to participate study. pupil diameter, contraction velocity, latency, amplitude, maximum gradient recovery time examined before, at 2 min 5 after cold pressor test, which was combined pupillary light reflex method. A brain 3D T1-weighted structural imaging scan, resting-state functional magnetic resonance diffusion tensor (DTI) scan also acquired.Patients exhibited a longer pressing compared control group (P < 0.01 P 0.05, respectively). There no significant difference blood pressure, or heart rate between two groups (all > 0.05). In group, regional homogeneity (ReHo) values left amygdala lateral hypothalamic area significantly higher than those other areas 0.001, Alphasim corrected). DTI whole showed lack indices, including FA, MD, AD, RD corrected).The may be related CM.