Rhein alleviates MPTP-induced Parkinson’s disease by suppressing neuroinflammation via MAPK/IκB pathway

• DOI: 10.3389/fnins.2024.1396345
• Publication Date: 2024-06-12T13:28:59Z
• Authors: Xin Qin; Shu Wang; Juan Huang; Binbin Hu; Xingyan Yang; Liying Liang; Rui Zhou; Wei Huang
• Keywords: MPTP

Parkinson's disease (PD) is a common neurodegenerative with rapid increase in incidence recent years. Existing treatments cannot slow or stop the progression of PD. It was proposed that neuroinflammation leads to neuronal death, making targeting promising therapeutic strategy. Our previous studies have demonstrated rhein protects neurons