Clinicopathological Features, Staging Classification, and Clinical Outcomes of Esophageal Melanoma: Evaluation of a Pooled Case Series

• DOI: 10.3389/fonc.2022.858145
• Publication Date: 2022-07-01T06:17:09Z
• Authors: Haiyan Sun; Ningning Zhu; Lei Gong; Lan Lan; Zhentao Yu; Zhanyu Pan
• Keywords: Cancer staging

Studies that have attempted to validate the staging systems and predictors of survival for patients with primary malignant melanoma esophagus (PMME) been underpowered given their scarcity small scale. We aimed review a large number PMME cases know more about its clinicopathological features, TNM systems, PMME. Case reports on were extracted from PubMed/Medline through bibliography search our center. A total 287 identified. The majority patient population was male (72.08%). most common location lower (50.62%) middle (35.39%). Among patients, 82.28% received surgical intervention. median overall (OS) duration 15 months (0.5-244). American Joint Commission Cancer classification (AJCC) mucosal upper aerodigestive tract stage IVB IVC integrated in IVA showed better distribution OS than esophageal carcinoma. T stage, N surgery had significant impacts univariate analysis. However, only identified as independent factors multivariate Cox models. is an aggressive tumor poor prognosis. AJCC system may be option patients. are OS.