Burden of breast cancer and attributable risk factors in the North Africa and Middle East region, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

• DOI: 10.3389/fonc.2023.1132816
• Publication Date: 2023-08-08T13:06:01Z
• Authors: Sina Azadnajafabad; Sahar Saeedi Mogh...; Esmaeil Mohammadi; Negar Rezaei; Mohammad-Mahdi Ra...; Nazila Rezaei; Ali H. Mokdad; Mohsen Naghavi; Christopher J. L....; Bagher Larijani; Farshad Farzadfar
• Keywords: Middle East; breast cancer; risk factor; Oncology; 610; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; epidemiology; North Africa; RC254-282; Global Burden of Disease

Breast cancer (BC) is the most common in women globally. The North Africa and Middle East (NAME) region coping hard with burden of BC. We aimed to present latest epidemiology BC its risk factors this region.We retrieved data on from Global Burden Disease Study 2019 describe status 21 countries NAME 1990 2019. explored incidence, prevalence, deaths, disability-adjusted life years (DALYs), attributable seven female BC, namely, alcohol use, diet high red meat, low physical activity, smoking, secondhand smoke, body mass index, fasting plasma glucose. Decomposition analysis incidence trend was done find out contributing cancer's growth.In 2019, there were 835,576 (95% uncertainty interval: 741,968 944,851) 10,938 (9,030 13,256) male prevalent cases region. This number leads 35,405 (30,676 40,571) deaths among patients 809 (654 1,002) year. responsible for 1,222,835 (1,053,073 1,411,009) DALYs a greater proportion (94.9%) lost (YLLs). major contributor increase past three decades found be age-specific rates (227.5%), compared population growth (73.8%) aging (81.8%). behavioral majority (DALYs: 106,026 [66,614 144,247]). High glucose factor largest effect 84,912 [17,377 192,838]) burden.The increasing remarkable, especially when considering limited resources developing Proper policies like expanding screening programs careful resource management are needed effectively manage burden.