Refractory and progressively worsening nasal obstruction: case report of nasal osteoblastoma and literature review

• DOI: 10.3389/fonc.2023.1168777
• Publication Date: 2023-07-15T03:21:47Z
• Authors: Caishan Fang; Ruizhi Wang; Min Zhou; Tengyu Chen; Qinxiu Zhang; Yan Ruan; Chunqiao Li
• Keywords: Osteoblastoma; Osteoma; Osteoid

Nasal osteoblastoma (OB) is a rare and locally aggressive osteogenic tumor that has rarely been reported, there lack of effective evidence data for its diagnosis treatment. In this study, we report 31-year-old female patient who presented with nasal congestion associated progressive painless swelling the left maxillofacial region. A preoperative computed tomography (CT) examination paranasal sinuses was performed, based on imaging presentation, surgeon unable to differentiate between OB, osteoid osteoma (OO), fibrous dysplasia bone (FDB) osteoblastic fibroma (OF). After excluding contraindications surgery, underwent endoscopic excision mass, which found be gravel-like difficult remove cleanly during operation. The mass brittle bled easily, resulting in inadequate exposure operative field, prolonged operation time, substantial intraoperative blood loss. This indicates definite (biopsy deeper parts recommended) appropriate preparations (e.g., angiography embolization, adequate preparation) are very important. frozen postoperative pathological results clearly identified as OB. No local recurrence observed at 11-month follow-up.