Peroral Endoscopic Myotomy for Pediatric Achalasia: A Retrospective Analysis of 21 Cases With a Minimum Follow-Up of 5 Years

• DOI: 10.3389/fped.2022.845103
• Publication Date: 2022-04-04T05:24:34Z
• Authors: Dongzi Peng; Yuyong Tan; Chenjie Li; Liang Lv; Hongyi Zhu; Chengbai Liang; Rong Li; Deliang Liu
• Keywords: Single Center

Background Peroral endoscopic myotomy (POEM) has shown promising short-term safety and efficacy in pediatric patients, while long-term outcomes are largely unknown. This study aimed to assess the clinical effects of POEM for achalasia who had a follow-up at least 5 years. Methods Pediatric patients from single center underwent between October 2011 November 2016 were, respectively, collected analyzed outcomes. Patients were contacted evaluate their current symptoms encouraged repeat endoscopy manometry. The success, procedure-related parameters, adverse events, gastroesophageal reflux disease after POEM, quality life evaluated. Results A total twenty-four our studied, with mean age 14.42 ± 2.65. Two 24 (8.3%) previous treatment. procedure time was 58.67 19.10 min, 8.3% (2/24) experienced perioperative events. symptom scores obtained 21 92.57 months, remainder lost 38 months. Eckardt significantly improved preoperative baseline (preoperative 7.67 1.62 vs. 0.86 1.28, P < 0.001). Long-term overall success achieved 95.8% none required retreatment symptoms. 12.5% suffered reflux. 76.2% expressed satisfaction POEM. No severe events observed during operation 5-years follow-up. Conclusion resulted successful symptomatic mitigation majority multi-center large-scale, prospective is necessary confirmed conclusion.