An unusual presentation of neonatal rhabdomyosarcoma: a case report

• DOI: 10.3389/fped.2023.1233334
• Publication Date: 2023-10-27T22:23:26Z
• Authors: Danielle Strah; Kelly Stanley; Kelsie Oatmen; Ranjit I. Kylat; Megan Dishop; Michelina de la Maza
• Keywords: Presentation (obstetrics)

A full-term infant with an unremarkable prenatal course presented at birth a large midline facial mass and smaller masses in the head neck. In addition, multiple diffuse flesh-colored nodules spread along all upper lower limbs. An extensive evaluation to cover broad differential diagnosis of infectious, lymphatic/vascular, oncologic etiology was undertaken. The initial suspicion confirmed by biopsy skin lesion as congenital alveolar rhabdomyosarcoma (RMS). RMS is most common soft tissue sarcoma that occurs childhood. However, neonatal exceedingly rare. infant's treatment included vincristine, dactinomycin, cyclophosphamide addition salvage ifosfamide etoposide, which were dose-adjusted for age. Herein, we present case who showed improvement before relapsing succumbing her disease 5 months review limited literature available on this rare condition newer regimens improved mortality rates performed.