Unraveling the complexity of Disorders of the Gut-Brain Interaction: the gut microbiota connection in children

• DOI: 10.3389/fped.2023.1283389
• Publication Date: 2024-02-16T04:24:23Z
• Authors: Dimas Rosa; Roberto Arturo Za...; Rodrigo Vazquez-F...
• Keywords: Gut–brain axis; Gut microbiome

“Disorders of Gut-Brain Interaction (DGBIs),” formerly referred to as “Functional Gastrointestinal Disorders (FGIDs),” encompass a prevalent array chronic or recurring gastrointestinal symptoms that notably impact the quality life for affected children and their families. Recent studies have elucidated intricate pathophysiology DGBIs, underscoring correlation with gut microbiota. This review seeks explore present comprehension microbiota's role in DGBI development. While other factors can contribute microbiota prominently influences onset progression these conditions. According Rome IV diagnostic criteria, prevalence is approximately 40% worldwide. The Foundation has diligently worked nearly three decades refine our DGBIs. By centering on microbiota, this sheds light potential therapeutic interventions potentially enhancing pediatric patients