Effectiveness of a novel bubble CPAP system for neonatal respiratory support at a referral hospital in the Philippines

• DOI: 10.3389/fped.2023.1323178
• Publication Date: 2023-12-18T09:07:31Z
• Authors: Paula Rauschendorf; Ghassan Bou Saba; Grace K. Meara; Navid Roodaki; Agustin Conde-Agu...; Daisy Evangeline ...; Thomas F. Burke
• Keywords: 03 medical and health sciences; neonatal mortality; respiratory support; 0302 clinical medicine; low-resource settings; CPAP therapy; preterm birth; neonatal intensive care unit; Pediatrics; RJ1-570

Aim To examine the impact of introducing and implementing Vayu bubble continuous positive airway pressure (bCPAP) system on neonatal survival respiratory outcomes in a intensive care unit (NICU) Philippines. Methods We compared clinical 1,024 neonates before to 979 after introduction bCPAP systems into NICU. The primary outcome was discharge. Adjusted odds ratios (aORs) with 95% confidence intervals (CIs) were calculated. Analyses undertaken separately for entire NICU population who received any form support. Results associated (1) significant reductions intubation (aOR: 0.75; CI: 0.58–0.96) use nasal intermittent positive-pressure ventilation (NIPPV) 0.69; 0.50–0.96) among (2) increase discharge 1.53; 1.09–2.17) 0.52; 0.38–0.71), surfactant administration 0.60; 0.40–0.89), NIPPV 0.36–0.76), composite adverse 0.42–0.84) Conclusion Philippines resulted improvement outcomes.