The GATE-RTion/IDEAL Independent Dose Calculation System for Light Ion Beam Therapy

• DOI: 10.3389/fphy.2021.704760
• Publication Date: 2021-08-11T07:59:23Z
• Authors: L. Grevillot; D. J. Boersma; H. Fuchs; M. Bolsa-Ferruz; L. Scheuchenpflug; D. Georg; G. Kronreif; M. Stock
• Keywords: DICOM

Patient specific quality assurance can be improved using an independent dose calculation system. In addition, the implementation of such a system may support light ion beam therapy facilities in reducing needs for time, by substituting some experimental patient-specific procedures calculation. The GATE-RTion-based IDEAL was developed this purpose. It built DICOM-in, DICOM-out fashion, easy integration into state-of-the-art technology-based workflow scanned therapy. This article describes system, followed its clinical at MedAustron proton and carbon beams. Medical physics acceptance commissioning steps are presented together with key results: 3D reference boxes, 97% points agreed within 5% from measurements. Experimental validation stopping powers real pig samples were between 1.8% 3.8% soft tissues. Finally, five cases described, i.e. two three treatments. Dosimetric benchmarking against TPS calculations discussed details. As expected, software evidenced limitations arising pencil algorithm available ions, especially presence air cavities. found to satisfy requirements delivery systems is being clinically implemented MedAustron. open-source code as well documentation released on OpenGATE collaboration website, thus allowing long term maintenance future upgrades based more widespread utilization.