Response of Bone Metabolism Markers to Ice Swimming in Regular Practitioners

• DOI: 10.3389/fphys.2021.731523
• Publication Date: 2021-12-01T07:47:51Z
• Authors: Shuai Mu; Yang Xia; Qijun Wu; Chao Ji; Huixu Dai; Ming Zhang; Jiao Jiao; Feng Shi; Shengye Liu; Guangbin Wang; Tao Shen; Ye Tian; Liqing Yang; Qin Fu; Yuhong Zhao
• Keywords: Bone remodeling; N-terminal telopeptide

Objective: Both exercise and cold exposure cause physiological stress they often occur in combination. However, the effects of during severe on variation bone metabolism humans have remained elusive. The aim this study was to investigate variations circulating markers after ice swimming (IS). Methods: Eighty-seven women men aged 42-84 years old were recruited perform regular IS activities. Serum parathyroid hormone (PTH), total calcium (Ca2+), phosphorus (Pi), magnesium (Mg2+), N-terminal osteocalcin (N-MID), propeptide procollagen 1 (TPINP), C-terminal telopeptide type collagen (β-CTX) measured 30 min before IS. Bone mineral content (BMC) density (BMD) assessed at lumbar spine 1-4 (L1-L4) femoral neck (FN). habits obtained from questionnaires 10-year probability osteoporotic fracture calculated using FRAX® tool with without a BMD value FN. Results: There significant increases PTH (median, 40.120-51.540 pg/mL), Ca2+ 2.330-2.400 mmol/L), Pi 1.100-1.340 mmol/L) decreases TPINP 38.190-36.610 ng/mL) β-CTX 0.185-0.171 ng/mL), while there trend for increased serum Mg2+ (P = 0.058) but no change N-MID 0.933) all subjects. proportions cases hyperparathyroidemia, hypercalcemia, hyperphosphatemia those performing statistically significant. baseline levels changes had associations osteoporosis status, these may be age sex dependent. Finally, correlations among markers. Conclusion: caused alterations metabolic markers, specifically, PTH, should raise concerns about potential cardiovascular health risks exercise. Additionally, divergence between elevation decline turnover, which shown special suggest therapeutic implications disorders.