The binding pocket properties were fundamental to functional diversification of the GDSL-type esterases/lipases gene family in cotton

• DOI: 10.3389/fpls.2022.1099673
• Publication Date: 2023-01-18T07:07:05Z
• Authors: Jianshe Wang; Haiyan Zhao; Yunfang Qu; Peng Yang; Jinling Huang
• Keywords: Neofunctionalization; Molecular evolution; Functional divergence; Functional Diversity

Cotton is one of the most important crops in world. GDSL-type esterases/lipases (GELPs) are widely present all kingdoms and play an essential role regulating plant growth, development, responses to abiotic biotic stresses. However, molecular mechanisms underlying this functional diversity remain unclear. Here, based on identification GELP gene family, we applied genetic evolution simulation techniques explore cotton species. A total 1502 genes were identified 10 Segmental duplication differences evolutionary rates leading causes increase number during for ecological adaptation. Structural analysis revealed that family has high structural diversity. Moreover, studies have demonstrated significant properties binding pockets among GELPs. In process adapting environment, GELPs not only segmental but also different rates, resulting This leads 3D structure pocket and, finally, These findings provide a reference further analyses