Potential impact of metabolic syndrome on cognitive function in US firefighters

• DOI: 10.3389/fpubh.2023.1150121
• Publication Date: 2023-05-25T04:30:19Z
• Authors: Myong-Won Seo; Joshua Gann; Jung-Min Lee; Kevin S. Heffernan; Joon Young Kim; Hyun Chul Jung
• Keywords: Male; Metabolic Syndrome; line-of-duty deaths; firefighter health; cognitive health; Cognition; Cardiovascular Diseases; Firefighters; occupational risk; Humans; Public Health; Public aspects of medicine; RA1-1270; Insulin Resistance; cardiometabolic disease risk

Among US firefighters, sudden cardiac arrest and psychological stress (i.e., PTSD) are the leading cause of on-duty death. Metabolic syndrome (MetSyn) may influence both cardiometabolic cognitive health. Here, we examined differences in disease risk factors, function, physical fitness firefighters with vs. without MetSyn.One hundred fourteen male aged 20 to 60 years, participated study. MetSyn non-MetSyn were divided by AHA/NHLBI criteria. Of them, performed a paired-match analysis respect age BMI (n = 18) 18). The factors included blood pressure, fasting glucose, lipid profiles [HDL-C, triglyceride (TG)], surrogate markers insulin resistance [TG/HDL-C, TG glucose index (TyG)]. test psychomotor vigilance task as measure reaction time delayed-match-to-sample (DMS) memory, using computer-based Psychological Experiment Building Language Version 2.0 program. between groups analyzed an independent t-test adjusted for BMI. In addition, Spearman correlation stepwise multiple regression conducted.US exhibited severe estimated TG/HDL-C TyG (Cohen's d > 0.8, all p < 0.01) compared their age- BMI-matched counterparts MetSyn. higher DMS total 0.01). linear regression, HDL-C predicted (β - 0.440, R2 0.194, 0.05), 0.432, 0.186, 0.05) time.US predisposed metabolic resistance, even when matched BMI, there was negative association characteristics function firefighters. findings this study suggest that prevention be beneficial supporting firefighters' safety occupational performance.